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Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling

Fibroblast growth factor (FGF)-23 induces hypertrophy and calcium (Ca(2+)) dysregulation in cardiomyocytes, leading to cardiac arrhythmia and heart failure. However, knowledge regarding the effects of FGF-23 on cardiac fibrogenesis remains limited. This study investigated whether FGF-23 modulates ca...

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Detalles Bibliográficos
Autores principales: Lee, Ting-Wei, Chung, Cheng-Chih, Lee, Ting-I, Lin, Yung-Kuo, Kao, Yu-Hsun, Chen, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745152/
https://www.ncbi.nlm.nih.gov/pubmed/35008591
http://dx.doi.org/10.3390/ijms23010166