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Proteasome Inhibitors Interrupt the Activation of Non-Canonical NF-κB Signaling Pathway and Induce Cell Apoptosis in Cytarabine-Resistant HL60 Cells

Over half of older patients with acute myeloid leukemia (AML) do not respond to cytotoxic chemotherapy, and most responders relapse because of drug resistance. Cytarabine is the main drug used for the treatment of AML. Intensive treatment with high-dose cytarabine can increase the overall survival r...

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Detalles Bibliográficos
Autores principales: Wang, Shuo-Yu, Shih, Yin-Hwa, Shieh, Tzong-Ming, Tseng, Yu-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745175/
https://www.ncbi.nlm.nih.gov/pubmed/35008789
http://dx.doi.org/10.3390/ijms23010361