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Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1
The Na/HCO(3) cotransporter NBCe1 is a member of SLC4A transporters that move HCO(3)(−) across cell membranes and regulate intracellular pH or transepithelial HCO(3) transport. NBCe1 is highly selective to HCO(3)(−) and does not transport other anions; the molecular mechanism of anion selectivity is...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745181/ https://www.ncbi.nlm.nih.gov/pubmed/35008963 http://dx.doi.org/10.3390/ijms23010532 |