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Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1

The Na/HCO(3) cotransporter NBCe1 is a member of SLC4A transporters that move HCO(3)(−) across cell membranes and regulate intracellular pH or transepithelial HCO(3) transport. NBCe1 is highly selective to HCO(3)(−) and does not transport other anions; the molecular mechanism of anion selectivity is...

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Detalles Bibliográficos
Autores principales:	Lee, Soojung, Lin, Jason, Choi, Inyeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745181/ https://www.ncbi.nlm.nih.gov/pubmed/35008963 http://dx.doi.org/10.3390/ijms23010532

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