Effect of Divalent Metal Ion on the Structure, Stability and Function of Klebsiella pneumoniae Nicotinate-Nucleotide Adenylyltransferase: Empirical and Computational Studies

The continuous threat of drug-resistant Klebsiella pneumoniae justifies identifying novel targets and developing effective antibacterial agents. A potential target is nicotinate nucleotide adenylyltransferase (NNAT), an indispensable enzyme in the biosynthesis of the cell-dependent metabolite, NAD(+...

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Detalles Bibliográficos
Autores principales: Jeje, Olamide, Maake, Reabetswe, van Deventer, Ruan, Esau, Veruschka, Iwuchukwu, Emmanuel Amarachi, Meyer, Vanessa, Khoza, Thandeka, Achilonu, Ikechukwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745210/
https://www.ncbi.nlm.nih.gov/pubmed/35008542
http://dx.doi.org/10.3390/ijms23010116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745210/
https://www.ncbi.nlm.nih.gov/pubmed/35008542
http://dx.doi.org/10.3390/ijms23010116

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