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Novel 1,3,5-Triazinyl Aminobenzenesulfonamides Incorporating Aminoalcohol, Aminochalcone and Aminostilbene Structural Motifs as Potent Anti-VRE Agents, and Carbonic Anhydrases I, II, VII, IX, and XII Inhibitors

A series of 1,3,5-triazinyl aminobenzenesulfonamides substituted by aminoalcohol, aminostilbene, and aminochalcone structural motifs was synthesized as potential human carbonic anhydrase (hCA) inhibitors. The compounds were evaluated on their inhibition of tumor-associated hCA IX and hCA XII, hCA VI...

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Detalles Bibliográficos
Autores principales: Havránková, Eva, Garaj, Vladimír, Mascaretti, Šárka, Angeli, Andrea, Soldánová, Zuzana, Kemka, Miroslav, Motyčka, Jozef, Brázdová, Marie, Csöllei, Jozef, Jampílek, Josef, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745223/
https://www.ncbi.nlm.nih.gov/pubmed/35008657
http://dx.doi.org/10.3390/ijms23010231