MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease

The interleukin-21 receptor (IL-21R) can be upregulated in endothelial cells (EC) from ischemic muscles in mice following hind-limb ischemia (HLI), an experimental peripheral arterial disease (PAD) model, blocking this ligand–receptor pathway-impaired STAT3 activation, angiogenesis, and perfusion re...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Yang, Liang, Yuan, Mingjie, Farber, Charles R., Spolski, Rosanne, Leonard, Warren J., Ganta, Vijay C., Annex, Brian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745227/
https://www.ncbi.nlm.nih.gov/pubmed/35008699
http://dx.doi.org/10.3390/ijms23010271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745227/
https://www.ncbi.nlm.nih.gov/pubmed/35008699
http://dx.doi.org/10.3390/ijms23010271

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