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MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease

The interleukin-21 receptor (IL-21R) can be upregulated in endothelial cells (EC) from ischemic muscles in mice following hind-limb ischemia (HLI), an experimental peripheral arterial disease (PAD) model, blocking this ligand–receptor pathway-impaired STAT3 activation, angiogenesis, and perfusion re...

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Detalles Bibliográficos
Autores principales:	Wang, Tao, Yang, Liang, Yuan, Mingjie, Farber, Charles R., Spolski, Rosanne, Leonard, Warren J., Ganta, Vijay C., Annex, Brian H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745227/ https://www.ncbi.nlm.nih.gov/pubmed/35008699 http://dx.doi.org/10.3390/ijms23010271

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