Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics

Bicalutamide (Bic) is an androgen deprivation therapy (ADT) for treating prostate cancer, while ADT is potentially associated with acute kidney injury. Previously, we recognized Bic induced renal mitochondria dysfunction in vitro and in vivo via the ROS -HIF1α pathway. Whether OXPHOS complex, as wel...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Chou, Chen, Chang-Rong, Chen, Chang-Yu, Peng, Chiung-Chi, Peng, Robert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745250/
https://www.ncbi.nlm.nih.gov/pubmed/35011880
http://dx.doi.org/10.3390/jcm11010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745250/
https://www.ncbi.nlm.nih.gov/pubmed/35011880
http://dx.doi.org/10.3390/jcm11010135

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