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Pros and Cons of Pharmacological Manipulation of cGMP-PDEs in the Prevention and Treatment of Breast Cancer

The cyclic nucleotides, cAMP and cGMP, are ubiquitous second messengers responsible for translating extracellular signals to intracellular biological responses in both normal and tumor cells. When these signals are aberrant or missing, cells may undergo neoplastic transformation or become resistant...

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Detalles Bibliográficos
Autores principales: Di Iorio, Patrizia, Ronci, Maurizio, Giuliani, Patricia, Caciagli, Francesco, Ciccarelli, Renata, Caruso, Vanni, Beggiato, Sarah, Zuccarini, Mariachiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745278/
https://www.ncbi.nlm.nih.gov/pubmed/35008687
http://dx.doi.org/10.3390/ijms23010262