ER Stress in ERp57 Knockout Knee Joint Chondrocytes Induces Osteoarthritic Cartilage Degradation and Osteophyte Formation

Ageing or obesity are risk factors for protein aggregation in the endoplasmic reticulum (ER) of chondrocytes. This condition is called ER stress and leads to induction of the unfolded protein response (UPR), which, depending on the stress level, restores normal cell function or initiates apoptotic c...

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Detalles Bibliográficos
Autores principales: Rellmann, Yvonne, Eidhof, Elco, Hansen, Uwe, Fleischhauer, Lutz, Vogel, Jonas, Clausen-Schaumann, Hauke, Aszodi, Attila, Dreier, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745280/
https://www.ncbi.nlm.nih.gov/pubmed/35008608
http://dx.doi.org/10.3390/ijms23010182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745280/
https://www.ncbi.nlm.nih.gov/pubmed/35008608
http://dx.doi.org/10.3390/ijms23010182

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