Novel Tetrazole-Based Antimicrobial Agents Targeting Clinical Bacteria Strains: Exploring the Inhibition of Staphylococcus aureus DNA Topoisomerase IV and Gyrase

Eleven novel imide-tetrazoles were synthesized. In the initial stage of research, in silico structure-based pharmacological prediction was conducted. All compounds were screened for antimicrobial activity using standard and clinical strains. Within the studied group, compounds 1–3 were recognized as...

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Detalles Bibliográficos
Autores principales: Roszkowski, Piotr, Szymańska-Majchrzak, Jolanta, Koliński, Michał, Kmiecik, Sebastian, Wrzosek, Małgorzata, Struga, Marta, Szulczyk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745314/
https://www.ncbi.nlm.nih.gov/pubmed/35008805
http://dx.doi.org/10.3390/ijms23010378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745314/
https://www.ncbi.nlm.nih.gov/pubmed/35008805
http://dx.doi.org/10.3390/ijms23010378

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