Synthesis of 3-Amino-4-substituted Monocyclic ß-Lactams—Important Structural Motifs in Medicinal Chemistry

Monocyclic ß-lactams (azetidin-2-ones) exhibit a wide range of biological activities, the most important of which are antibacterial, anticancer, and cholesterol absorption inhibitory activities. The synthesis of decorated monocyclic ß-lactams is challenging because their ring is highly constrained a...

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Detalles Bibliográficos
Autores principales: Grabrijan, Katarina, Strašek, Nika, Gobec, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745335/
https://www.ncbi.nlm.nih.gov/pubmed/35008788
http://dx.doi.org/10.3390/ijms23010360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745335/
https://www.ncbi.nlm.nih.gov/pubmed/35008788
http://dx.doi.org/10.3390/ijms23010360

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