In Vitro and In Silico Kinetic Studies of Patented 1,7-diEthyl and 1,7-diMethyl Aminoalkanol Derivatives as New Inhibitors of Acetylcholinesterase

Two aminoalkanol derivatives of 1,7-diEthyl-8,9-diphenyl-4azatricyclo (5.2.1.02.6) dec-8-ene-3,5,10-trione and two derivatives of 1,7-diMethyl-8,9-diphenyl-4-azatricyclo (5.2.1.02.6) dec-8-ene-3,5,10-trione were evaluated in vitro for their inhibition efficacy of acetylcholinesterase. The Km, Vmax,...

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Detalles Bibliográficos
Autores principales: Grodner, Błażej, Napiórkowska, Mariola, Pisklak, Dariusz Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745342/
https://www.ncbi.nlm.nih.gov/pubmed/35008697
http://dx.doi.org/10.3390/ijms23010270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745342/
https://www.ncbi.nlm.nih.gov/pubmed/35008697
http://dx.doi.org/10.3390/ijms23010270

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