The Influence of Mitochondrial-DNA-Driven Inflammation Pathways on Macrophage Polarization: A New Perspective for Targeted Immunometabolic Therapy in Cerebral Ischemia-Reperfusion Injury

Cerebral ischemia-reperfusion injury is related to inflammation driven by free mitochondrial DNA. At the same time, the pro-inflammatory activation of macrophages, that is, polarization in the M1 direction, aggravates the cycle of inflammatory damage. They promote each other and eventually transform...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Sihang, Fu, Jiaying, Wang, Jian, Zhao, Yuanxin, Liu, Buhan, Wei, Jiahang, Yan, Xiaoyu, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745401/
https://www.ncbi.nlm.nih.gov/pubmed/35008558
http://dx.doi.org/10.3390/ijms23010135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745401/
https://www.ncbi.nlm.nih.gov/pubmed/35008558
http://dx.doi.org/10.3390/ijms23010135

Ejemplares similares