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The Influence of Mitochondrial-DNA-Driven Inflammation Pathways on Macrophage Polarization: A New Perspective for Targeted Immunometabolic Therapy in Cerebral Ischemia-Reperfusion Injury

Cerebral ischemia-reperfusion injury is related to inflammation driven by free mitochondrial DNA. At the same time, the pro-inflammatory activation of macrophages, that is, polarization in the M1 direction, aggravates the cycle of inflammatory damage. They promote each other and eventually transform...

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Detalles Bibliográficos
Autores principales:	Yu, Sihang, Fu, Jiaying, Wang, Jian, Zhao, Yuanxin, Liu, Buhan, Wei, Jiahang, Yan, Xiaoyu, Su, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745401/ https://www.ncbi.nlm.nih.gov/pubmed/35008558 http://dx.doi.org/10.3390/ijms23010135

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