Lipofuscin Granule Bisretinoid Oxidation in the Human Retinal Pigment Epithelium forms Cytotoxic Carbonyls

Age-related macular degeneration (AMD) is the primary cause of central blindness among the elderly. AMD is associated with progressive accumulation of lipofuscin granules in retinal pigment epithelium (RPE) cells. Lipofuscin contains bisretinoid fluorophores, which are photosensitizers and are photo...

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Detalles Bibliográficos
Autores principales: Yakovleva, Marina, Dontsov, Alexander, Trofimova, Natalia, Sakina, Natalia, Kononikhin, Alexey, Aybush, Arseny, Gulin, Alexander, Feldman, Tatiana, Ostrovsky, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745408/
https://www.ncbi.nlm.nih.gov/pubmed/35008647
http://dx.doi.org/10.3390/ijms23010222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745408/
https://www.ncbi.nlm.nih.gov/pubmed/35008647
http://dx.doi.org/10.3390/ijms23010222

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