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Dopamine and Methamphetamine Differentially Affect Electron Transport Chain Complexes and Parkin in Rat Striatum: New Insight into Methamphetamine Neurotoxicity

Methamphetamine (METH) is a highly abused psychostimulant that is neurotoxic to dopaminergic (DAergic) nerve terminals in the striatum and increases the risk of developing Parkinson’s disease (PD). In vivo, METH-mediated DA release, followed by DA-mediated oxidative stress and mitochondrial dysfunct...

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Detalles Bibliográficos
Autores principales: Bazylianska, Viktoriia, Sharma, Akhil, Chauhan, Heli, Schneider, Bernard, Moszczynska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745447/
https://www.ncbi.nlm.nih.gov/pubmed/35008791
http://dx.doi.org/10.3390/ijms23010363