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Downregulation of Methionine Cycle Genes MAT1A and GNMT Enriches Protein-Associated Translation Process and Worsens Hepatocellular Carcinoma Prognosis

The major biological methyl donor, S-adenosylmethionine (adoMet) synthesis occurs mainly in the liver. Methionine adenosyltransferase 1A (MAT1A) and glycine N-methyltransferase (GNMT) are two key enzymes involved in the functional implications of that variation. We collected 42 RNA-seq data from pai...

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Detalles Bibliográficos
Autores principales: Chen, Po-Ming, Tsai, Cheng-Hsueh, Huang, Chieh-Cheng, Hwang, Hau-Hsuan, Li, Jian-Rong, Liu, Chun-Chi, Ko, Hsin-An, Chiang, En-Pei Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745498/
https://www.ncbi.nlm.nih.gov/pubmed/35008908
http://dx.doi.org/10.3390/ijms23010481