Modulation by 17,20S(OH)(2)pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis

We previously demonstrated that the non-calcemic pregnacalciferol (pD) analog 17,20S (OH)(2)pD suppressed TGF-β1-induced type I collagen production in cultured normal human dermal fibroblasts. In the present studies, we examined fibroblasts cultured from the lesional skin of patients with systemic s...

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Detalles Bibliográficos
Autores principales: Brown Lobbins, Monica L., Slominski, Andrzej T., Hasty, Karen A., Zhang, Sicheng, Miller, Duane D., Li, Wei, Kim, Tae-Kang, Janjetovic, Zorica, Tuckey, Robert C., Scott, Imara-Safi O., Myers, Linda K., Postlethwaite, Arnold E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745512/
https://www.ncbi.nlm.nih.gov/pubmed/35008794
http://dx.doi.org/10.3390/ijms23010367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745512/
https://www.ncbi.nlm.nih.gov/pubmed/35008794
http://dx.doi.org/10.3390/ijms23010367

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