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Availability of Arg, but Not tRNA, Is a Rate-Limiting Factor for Intracellular Arginylation

Protein arginylation, mediated by arginyltransferase ATE1, is a posttranslational modification of emerging biological importance that consists of transfer of the amino acid Arg from tRNA to protein and peptide targets. ATE1 can bind tRNA and exhibits specificity toward particular tRNA types, but its...

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Detalles Bibliográficos
Autores principales: Avcilar-Kucukgoze, Irem, MacTaggart, Brittany, Kashina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745564/
https://www.ncbi.nlm.nih.gov/pubmed/35008737
http://dx.doi.org/10.3390/ijms23010314