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Is Protein Folding a Thermodynamically Unfavorable, Active, Energy-Dependent Process?
The prevailing current view of protein folding is the thermodynamic hypothesis, under which the native folded conformation of a protein corresponds to the global minimum of Gibbs free energy G. We question this concept and show that the empirical evidence behind the thermodynamic hypothesis of foldi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745595/ https://www.ncbi.nlm.nih.gov/pubmed/35008947 http://dx.doi.org/10.3390/ijms23010521 |