A Necessary Role for Increased Biglycan Expression during L1-Mediated Colon Cancer Progression

Aberrant activation of Wnt/β-catenin signaling and downstream β-catenin-TCF target genes is a hallmark of colorectal cancer (CRC) development. We identified the immunoglobulin-like cell adhesion receptor L1CAM (L1) as a target of β-catenin-TCF transactivation in CRC cells. Overexpression of L1 in CR...

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Detalles Bibliográficos
Autores principales: Saha, Arka, Cheriyamundath, Sanith, Kumar, Anmol, Gavert, Nancy, Brabletz, Thomas, Ben-Ze’ev, Avri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745639/
https://www.ncbi.nlm.nih.gov/pubmed/35008869
http://dx.doi.org/10.3390/ijms23010445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745639/
https://www.ncbi.nlm.nih.gov/pubmed/35008869
http://dx.doi.org/10.3390/ijms23010445

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