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Altered HIV-1 mRNA Splicing Due to Drug-Resistance-Associated Mutations in Exon 2/2b

The underlying molecular mechanism and their general effect on the replication capacity of HIV 1 drug-resistance-associated mutations is often poorly understood. To elucidate the effect of two such mutations located in a region with a high density of spicing regulatory elements on the HIV-1-splicing...

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Detalles Bibliográficos
Autores principales: Müller, Lisa, Moskorz, Wiebke, Brillen, Anna-Lena, Hillebrand, Frank, Ostermann, Philipp Niklas, Kiel, Niklas, Walotka, Lara, Ptok, Johannes, Timm, Jörg, Lübke, Nadine, Schaal, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745674/
https://www.ncbi.nlm.nih.gov/pubmed/35008581
http://dx.doi.org/10.3390/ijms23010156