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TdIF1-LSD1 Axis Regulates Epithelial—Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer

We have previously found that TdT-interacting factor 1 (TdIF1) is a potential oncogene expressed in non-small cell lung cancer (NSCLC) and is associated with poor prognosis. However, its exact mechanism is still unclear. The lysine-specific demethylase 1 (LSD1) is a crucial mediator of the epithelia...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Xiong, Juan, Xu, Derong, Hao, Nan, Zhang, Yujuan, Sang, Yi, Wang, Zhigang, Zheng, Xiufen, Min, Jeffrey, Diao, Hong, Raphael, Jacques, Vareki, Saman Maleki, Koropatnick, James, Min, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745707/
https://www.ncbi.nlm.nih.gov/pubmed/35008676
http://dx.doi.org/10.3390/ijms23010250