Neurofibromatosis Type 1 Gene Alterations Define Specific Features of a Subset of Glioblastomas

Neurofibromatosis type 1 (NF1) gene mutations or alterations occur within neurofibromatosis type 1 as well as in many different malignant tumours on the somatic level. In glioblastoma, NF1 loss of function plays a major role in inducing the mesenchymal (MES) subtype and, therefore defining the most...

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Detalles Bibliográficos
Autores principales: Scheer, Maximilian, Leisz, Sandra, Sorge, Eberhard, Storozhuk, Olha, Prell, Julian, Ho, Ivy, Harder, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745708/
https://www.ncbi.nlm.nih.gov/pubmed/35008787
http://dx.doi.org/10.3390/ijms23010352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745708/
https://www.ncbi.nlm.nih.gov/pubmed/35008787
http://dx.doi.org/10.3390/ijms23010352

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