Exploring the Catalytic Mechanism of the RNA Cap Modification by nsp16-nsp10 Complex of SARS-CoV-2 through a QM/MM Approach

The inhibition of key enzymes that may contain the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have assumed central importance in drug discovery projects. Nonstructural proteins (nsps) are essential for RNA capping and coronavirus replication since it protects t...

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Detalles Bibliográficos
Autores principales: Silva, José Rogério A., Urban, Jaime, Araújo, Edson, Lameira, Jerônimo, Moliner, Vicent, Alves, Cláudio Nahum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745711/
https://www.ncbi.nlm.nih.gov/pubmed/35008724
http://dx.doi.org/10.3390/ijms23010300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745711/
https://www.ncbi.nlm.nih.gov/pubmed/35008724
http://dx.doi.org/10.3390/ijms23010300

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