Autoantibodies Targeting AT(1)- and ET(A)-Receptors Link Endothelial Proliferation and Coagulation via Ets-1 Transcription Factor

Scleroderma renal crisis (SRC) is an acute life-threatening manifestation of systemic sclerosis (SSc) caused by obliterative vasculopathy and thrombotic microangiopathy. Evidence suggests a pathogenic role of immunoglobulin G (IgG) targeting G-protein coupled receptors (GPCR). We therefore dissected...

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Detalles Bibliográficos
Autores principales: Catar, Rusan, Herse-Naether, Melanie, Zhu, Nan, Wagner, Philine, Wischnewski, Oskar, Kusch, Angelika, Kamhieh-Milz, Julian, Eisenreich, Andreas, Rauch, Ursula, Hegner, Björn, Heidecke, Harald, Kill, Angela, Riemekasten, Gabriela, Kleinau, Gunnar, Scheerer, Patrick, Dragun, Duska, Philippe, Aurelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745726/
https://www.ncbi.nlm.nih.gov/pubmed/35008670
http://dx.doi.org/10.3390/ijms23010244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745726/
https://www.ncbi.nlm.nih.gov/pubmed/35008670
http://dx.doi.org/10.3390/ijms23010244

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