Cancer-Homing CAR-T Cells and Endogenous Immune Population Dynamics

Chimeric antigen receptor (CAR) therapy is based on patient blood-derived T cells and natural killer cells, which are engineered in vitro to recognize a target antigen in cancer cells. Most CAR-T recognize target antigens through immunoglobulin antigen-binding regions. Hence, CAR-T cells do not requ...

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Detalles Bibliográficos
Autores principales: Guerra, Emanuela, Di Pietro, Roberta, Basile, Mariangela, Trerotola, Marco, Alberti, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745734/
https://www.ncbi.nlm.nih.gov/pubmed/35008832
http://dx.doi.org/10.3390/ijms23010405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745734/
https://www.ncbi.nlm.nih.gov/pubmed/35008832
http://dx.doi.org/10.3390/ijms23010405

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