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Cancer-Homing CAR-T Cells and Endogenous Immune Population Dynamics

Chimeric antigen receptor (CAR) therapy is based on patient blood-derived T cells and natural killer cells, which are engineered in vitro to recognize a target antigen in cancer cells. Most CAR-T recognize target antigens through immunoglobulin antigen-binding regions. Hence, CAR-T cells do not requ...

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Detalles Bibliográficos
Autores principales:	Guerra, Emanuela, Di Pietro, Roberta, Basile, Mariangela, Trerotola, Marco, Alberti, Saverio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745734/ https://www.ncbi.nlm.nih.gov/pubmed/35008832 http://dx.doi.org/10.3390/ijms23010405

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