Preparation and In Vitro Evaluation of RITUXfab-Decorated Lipoplexes to Improve Delivery of siRNA Targeting C1858T PTPN22 Variant in B Lymphocytes

Autoimmune endocrine disorders, such as type 1 diabetes (T1D) and thyroiditis, at present are treated with only hormone replacement therapy. This emphasizes the need to identify personalized effective immunotherapeutic strategies targeting T and B lymphocytes. Among the genetic variants associated w...

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Detalles Bibliográficos
Autores principales: Arena, Andrea, Belcastro, Eugenia, Accardo, Antonella, Sandomenico, Annamaria, Pagliarosi, Olivia, Rosa, Elisabetta, Petrini, Stefania, Conti, Libenzio Adrian, Giorda, Ezio, Corsetti, Tiziana, Schiaffini, Riccardo, Morelli, Giancarlo, Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745767/
https://www.ncbi.nlm.nih.gov/pubmed/35008834
http://dx.doi.org/10.3390/ijms23010408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745767/
https://www.ncbi.nlm.nih.gov/pubmed/35008834
http://dx.doi.org/10.3390/ijms23010408

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