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Relationships between type 2 diabetes, cell dysfunction, and redox signaling: A meta‐analysis of single‐cell gene expression of human pancreatic α‐ and β‐cells

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by insulin resistance and failure of β‐cells to meet the metabolic demand for insulin. Recent advances in single‐cell RNA sequencing (sc‐RNA‐Seq) have allowed for in‐depth studies to further understand the underlying cell...

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Detalles Bibliográficos
Autores principales: Marques, Emily Sara, Formato, Emily, Liang, Wenle, Leonard, Emily, Timme‐Laragy, Alicia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746116/
https://www.ncbi.nlm.nih.gov/pubmed/34725923
http://dx.doi.org/10.1111/1753-0407.13236