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Braiding Braak and Braak: Staging patterns and model selection in network neurodegeneration

A hallmark of Alzheimer’s disease is the aggregation of insoluble amyloid-beta plaques and tau protein neurofibrillary tangles. A key histopathological observation is that tau protein aggregates follow a structured progression pattern through the brain. Mathematical network models of prion-like prop...

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Detalles Bibliográficos
Autores principales: Putra, Prama, Thompson, Travis B., Chaggar, Pavanjit, Goriely, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MIT Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746141/
https://www.ncbi.nlm.nih.gov/pubmed/35024537
http://dx.doi.org/10.1162/netn_a_00208