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Braiding Braak and Braak: Staging patterns and model selection in network neurodegeneration
A hallmark of Alzheimer’s disease is the aggregation of insoluble amyloid-beta plaques and tau protein neurofibrillary tangles. A key histopathological observation is that tau protein aggregates follow a structured progression pattern through the brain. Mathematical network models of prion-like prop...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MIT Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746141/ https://www.ncbi.nlm.nih.gov/pubmed/35024537 http://dx.doi.org/10.1162/netn_a_00208 |