Biophysical Evaluation and In Vitro Controlled Release of Two Isomeric Adamantane Phenylalkylamines with Antiproliferative/Anticancer and Analgesic Activity

The aqueous dissolution profile of the isomeric synthetic adamantane phenylalkylamine hydrochlorides I and II was probed. These adducts have shown significant antiproliferative/anticancer activity associated with an analgesic profile against neuropathic pain. They are both devoid of toxic effects an...

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Detalles Bibliográficos
Autores principales: Vlachou, Marilena, Foscolos, Angeliki-Sofia, Siamidi, Angeliki, Syriopoulou, Angeliki, Georgiou, Nikitas, Dedeloudi, Aikaterini, Tsiailanis, Antonis D., Tzakos, Andreas G., Mavromoustakos, Thomas, Papanastasiou, Ioannis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746252/
https://www.ncbi.nlm.nih.gov/pubmed/35011245
http://dx.doi.org/10.3390/molecules27010007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746252/
https://www.ncbi.nlm.nih.gov/pubmed/35011245
http://dx.doi.org/10.3390/molecules27010007

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