Biophysical Characterization of Novel DNA Aptamers against K103N/Y181C Double Mutant HIV-1 Reverse Transcriptase

The human immunodeficiency virus type-1 Reverse Transcriptase (HIV-1 RT) plays a pivotal role in essential viral replication and is the main target for antiviral therapy. The anti-HIV-1 RT drugs address resistance-associated mutations. This research focused on isolating the potential specific DNA ap...

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Detalles Bibliográficos
Autores principales: Ratanabunyong, Siriluk, Seetaha, Supaphorn, Hannongbua, Supa, Yanaka, Saeko, Yagi-Utsumi, Maho, Kato, Koichi, Paemanee, Atchara, Choowongkomon, Kiattawee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746315/
https://www.ncbi.nlm.nih.gov/pubmed/35011517
http://dx.doi.org/10.3390/molecules27010285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746315/
https://www.ncbi.nlm.nih.gov/pubmed/35011517
http://dx.doi.org/10.3390/molecules27010285

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