Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity

Development of novel anticancer therapeutic candidates is one of the key challenges in medicinal chemistry. Podophyllotoxin and its derivatives, as a potent cytotoxic agent, have been at the center of extensive chemical amendment and pharmacological investigation. Herein, a new series of podophyllot...

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Detalles Bibliográficos
Autores principales: Yang, Zhongtao, Zhou, Zitong, Luo, Xiai, Luo, Xiaoling, Luo, Hui, Luo, Lianxiang, Yang, Weiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746343/
https://www.ncbi.nlm.nih.gov/pubmed/35011453
http://dx.doi.org/10.3390/molecules27010220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746343/
https://www.ncbi.nlm.nih.gov/pubmed/35011453
http://dx.doi.org/10.3390/molecules27010220

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