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The Structural Basis of Peptide Binding at Class A G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the members of this family endogenously bind flexible pe...

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Detalles Bibliográficos
Autores principales: Vu, Oanh, Bender, Brian Joseph, Pankewitz, Lisa, Huster, Daniel, Beck-Sickinger, Annette G., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746363/
https://www.ncbi.nlm.nih.gov/pubmed/35011444
http://dx.doi.org/10.3390/molecules27010210