Cargando…
The Structural Basis of Peptide Binding at Class A G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the members of this family endogenously bind flexible pe...
Autores principales: | Vu, Oanh, Bender, Brian Joseph, Pankewitz, Lisa, Huster, Daniel, Beck-Sickinger, Annette G., Meiler, Jens |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746363/ https://www.ncbi.nlm.nih.gov/pubmed/35011444 http://dx.doi.org/10.3390/molecules27010210 |
Ejemplares similares
-
Improved in Vitro Folding of the Y(2) G Protein-Coupled Receptor into Bicelles
por: Schmidt, Peter, et al.
Publicado: (2018) -
Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor
por: Yang, Zhenlin, et al.
Publicado: (2018) -
Shuttling of Peptide‐Drug Conjugates by G Protein‐Coupled Receptors Is Significantly Improved by Pulsed Application
por: Ziffert, Isabelle, et al.
Publicado: (2020) -
Molecular basis for the evolved instability of a human G-protein coupled receptor
por: Chamness, Laura M., et al.
Publicado: (2021) -
Integrating Solid-State NMR and Computational Modeling to Investigate the Structure and Dynamics of Membrane-Associated Ghrelin
por: Vortmeier, Gerrit, et al.
Publicado: (2015)