Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode

The enantioseparation of four phthalimide derivatives (thalidomide, pomalidomide, lenalidomide and apremilast) was investigated on five different polysaccharide-type stationary phases (Chiralpak AD, Chiralpak AS, Lux Amylose-2, Chiralcel OD and Chiralcel OJ-H) using neat methanol (MeOH), ethanol (Et...

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Detalles Bibliográficos
Autores principales: Foroughbakhshfasaei, Mohammadhassan, Dobó, Máté, Boda, Francisc, Szabó, Zoltán-István, Tóth, Gergő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746373/
https://www.ncbi.nlm.nih.gov/pubmed/35011343
http://dx.doi.org/10.3390/molecules27010111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746373/
https://www.ncbi.nlm.nih.gov/pubmed/35011343
http://dx.doi.org/10.3390/molecules27010111

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