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Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode
The enantioseparation of four phthalimide derivatives (thalidomide, pomalidomide, lenalidomide and apremilast) was investigated on five different polysaccharide-type stationary phases (Chiralpak AD, Chiralpak AS, Lux Amylose-2, Chiralcel OD and Chiralcel OJ-H) using neat methanol (MeOH), ethanol (Et...
Autores principales: | Foroughbakhshfasaei, Mohammadhassan, Dobó, Máté, Boda, Francisc, Szabó, Zoltán-István, Tóth, Gergő |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746373/ https://www.ncbi.nlm.nih.gov/pubmed/35011343 http://dx.doi.org/10.3390/molecules27010111 |
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