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In Vivo Anticancer Activity of AZD3965: A Systematic Review

Proliferating cancer cells have high energy demands, which is mainly obtained through glycolysis. The transmembrane trafficking of lactate, a major metabolite produced by glycolytic cancer cells, relies on monocarboxylate transporters (MCTs). MCT1 optimally imports lactate, although it can work bidi...

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Detalles Bibliográficos
Autores principales: Silva, Ana, Antunes, Beatriz, Batista, Alberta, Pinto-Ribeiro, Filipa, Baltazar, Fátima, Afonso, Julieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746498/
https://www.ncbi.nlm.nih.gov/pubmed/35011413
http://dx.doi.org/10.3390/molecules27010181