Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

A number of pyrrolo[2,3-c]pyridines, pyrrolo[3,2-d]pyrimidines and pyrazolo[4,3-d]pyrimidines were designed and synthesized as antiproliferative agents. The target compounds possessed selected substituents in analogous positions on the central scaffold that allowed the extraction of interesting SARs...

Descripción completa

Detalles Bibliográficos
Autores principales: Dimitrakis, Spyridon, Gavriil, Efthymios-Spyridon, Pousias, Athanasios, Lougiakis, Nikolaos, Marakos, Panagiotis, Pouli, Nicole, Gioti, Katerina, Tenta, Roxane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746528/
https://www.ncbi.nlm.nih.gov/pubmed/35011476
http://dx.doi.org/10.3390/molecules27010247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746528/
https://www.ncbi.nlm.nih.gov/pubmed/35011476
http://dx.doi.org/10.3390/molecules27010247

Ejemplares similares