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Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach

Before entering the cell, the SARS-CoV-2 spike glycoprotein receptor-binding domain (RBD) binds to the human angiotensin-converting enzyme 2 (hACE2) receptor. Hence, this RBD is a critical target for the development of antiviral agents. Recent studies have discovered that SARS-CoV-2 variants with mu...

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Detalles Bibliográficos
Autores principales: Tallei, Trina Ekawati, Fatimawali, Adam, Ahmad Akroman, Elseehy, Mona M., El-Shehawi, Ahmed M., Mahmoud, Eman A., Tania, Adinda Dwi, Niode, Nurdjannah Jane, Kusumawaty, Diah, Rahimah, Souvia, Effendi, Yunus, Idroes, Rinaldi, Celik, Ismail, Hossain, Md. Jamal, Emran, Talha Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746556/
https://www.ncbi.nlm.nih.gov/pubmed/35011492
http://dx.doi.org/10.3390/molecules27010260