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GIF-2209, an Oxindole Derivative, Accelerates Melanogenesis and Melanosome Secretion via the Modification of Lysosomes in B16F10 Mouse Melanoma Cells

Melanogenesis and melanosome secretion are regulated by several mechanisms. In this study, we found that the oxindole derivative GIF-2209 accelerated melanogenesis associated with the discrimination in the expression and intracellular distributions of two melanogenic enzymes, tyrosinase (TYR) and ty...

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Detalles Bibliográficos
Autores principales: Watanabe, Miyu, Kawaguchi, Kyoka, Nakamura, Yusuke, Furuta, Kyoji, Takemori, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746627/
https://www.ncbi.nlm.nih.gov/pubmed/35011407
http://dx.doi.org/10.3390/molecules27010177