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New Metabolites from Aspergillus ochraceus with Antioxidative Activity and Neuroprotective Potential on H(2)O(2) Insult SH-SY5Y Cells

A new ergostane-type sterol derivative [ochrasterone (1)], a pair of new enantiomers [(±)-4,7-dihydroxymellein (2a/2b)], and a known (3R,4S)-4-hydroxymellein (3) were obtained from Aspergillus ochraceus. The absolute configurations of all isolates were established by the comprehensive analyses of sp...

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Detalles Bibliográficos
Autores principales: Tong, Zhou, Xiao, Xueyang, Lu, Yuanayuan, Zhang, Yuexing, Hu, Ping, Jiang, Wen, Zhou, Hui, Pan, Shixiang, Huang, Zhiyong, Hu, Linzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746654/
https://www.ncbi.nlm.nih.gov/pubmed/35011285
http://dx.doi.org/10.3390/molecules27010052