A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancer characterized by drug resistance, urging new therapeutic strategies. In recent years, protein kinases have emerged as promising pharmacological targets for the treatment of several solid and hematological tumors. Interestingly...

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Detalles Bibliográficos
Autores principales: Pecoraro, Camilla, Parrino, Barbara, Cascioferro, Stella, Puerta, Adrian, Avan, Amir, Peters, Godefridus J., Diana, Patrizia, Giovannetti, Elisa, Carbone, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746667/
https://www.ncbi.nlm.nih.gov/pubmed/35011251
http://dx.doi.org/10.3390/molecules27010019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746667/
https://www.ncbi.nlm.nih.gov/pubmed/35011251
http://dx.doi.org/10.3390/molecules27010019

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