Eco-Friendly, Simple, Fast, and Sensitive UPLC-MS/MS Method for Determination of Pexidartinib in Plasma and Its Application to Metabolic Stability

Pexidartinib is the first drug approved by the U.S. Food and Drug Administration specifically to treat the rare joint tumor tenosynovial giant cell tumor. In the current study, a validated, selective, and sensitive UPLC-MS/MS assay was developed for the quantitative determination of pexidartinib in...

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Detalles Bibliográficos
Autores principales: Ezzeldin, Essam, Iqbal, Muzaffar, Asiri, Yousif A., Mostafa, Gamal A. E., Sayed, Ahmed Y. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746680/
https://www.ncbi.nlm.nih.gov/pubmed/35011540
http://dx.doi.org/10.3390/molecules27010297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746680/
https://www.ncbi.nlm.nih.gov/pubmed/35011540
http://dx.doi.org/10.3390/molecules27010297

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