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Eco-Friendly, Simple, Fast, and Sensitive UPLC-MS/MS Method for Determination of Pexidartinib in Plasma and Its Application to Metabolic Stability
Pexidartinib is the first drug approved by the U.S. Food and Drug Administration specifically to treat the rare joint tumor tenosynovial giant cell tumor. In the current study, a validated, selective, and sensitive UPLC-MS/MS assay was developed for the quantitative determination of pexidartinib in...
Autores principales: | Ezzeldin, Essam, Iqbal, Muzaffar, Asiri, Yousif A., Mostafa, Gamal A. E., Sayed, Ahmed Y. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746680/ https://www.ncbi.nlm.nih.gov/pubmed/35011540 http://dx.doi.org/10.3390/molecules27010297 |
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