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Highly Selective Synthesis of 6-Glyoxylamidoquinoline Derivatives via Palladium-Catalyzed Aminocarbonylation

The aminocarbonylation of 6-iodoquinoline has been investigated in the presence of large series of amine nucleophiles, providing an efficient synthetic route for producing various quinoline-6-carboxamide and quinoline-6-glyoxylamide derivatives. It was shown, after detailed optimization study, that...

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Detalles Bibliográficos
Autores principales: Chniti, Sami, Kollár, László, Bényei, Attila, Takács, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746719/
https://www.ncbi.nlm.nih.gov/pubmed/35011236
http://dx.doi.org/10.3390/molecules27010004